Nusa Penida (Balinese: ᬦᬸᬲᬧᭂᬦᬶᬤ), romanized: nusapĕnida, lit. 'Penida Island') is an island located near the southeastern Indonesian island of Bali and a district of Klungkung Regency that includes the neighbouring small island of Nusa Lembongan and twelve even smaller islands. The Badung Strait separates the island and Bali. The interior of Nusa Penida is hilly with a maximum altitude of 524 metres. It is drier than the nearby island of Bali. It is one of the major tourist attractions among the three Nusa islands.

There are thirteen small islands nearby – Nusa Lembongan, Nusa Ceningan and eleven even smaller – which are included within the administrative district (kecamatan), which has the same name as the main island. It had a population of 45,110 at the 2010 census, covering 202.84 km², and the official estimate as at mid 2022 was 59,900.