The National Museum of Anthropology (Spanish: Museo Nacional de Antropología, MNA) is a national museum of Mexico. It is the largest and most visited museum in Mexico. Located in the area between Paseo de la Reforma and Mahatma Gandhi Street within Chapultepec Park in Mexico City, the museum contains significant archaeological and anthropological artifacts from Mexico's pre-Columbian heritage, such as the Stone of the Sun (or the Aztec calendar stone) and the Aztec Xochipilli statue.

The museum (along with many other Mexican national and regional museums) is managed by the Instituto Nacional de Antropología e Historia (National Institute of Anthropology and History), or INAH. It was one of several museums opened by Mexican President Adolfo López Mateos in 1964.

Assessments of the museum vary, with one considering it "a national treasure and a symbol of identity. The museum is the synthesis of an ideological, scientific, and political feat." Octavio Paz criticized the museum's making the Mexica (Aztec) hall central, saying the "exaltation and glorification of Mexico-Tenochtitlan transforms the Museum of Anthropology into a temple."