Occupied for thousands of years, the Chinguetti region was once a broad savannah; rock paintings at Agrour Amogjar, in the nearby Amogjar Pass, feature images of giraffes, cows, and people in a green landscape. It is quite different from the sand dunes of the surrounding desert, which make up most of the region today.[1]

The city was founded in AD 777. The name Chinguetti means "spring of horses" in the Azayr language, an extinct dialect of Soninke that was heavily mixed with Berber. The area, at that time far more green than today, was home to agricultural peoples ancestral to several sub-Saharan ethnic groups, including the Soninke.[2] : 15, 71 

By the 11th century, Chinguetti had become a trading center for a confederation of Berber tribes, known as the Sanhaja. They eventually melded with the Almoravids, represented by Abdallah ibn Yasin, who would eventually control an empire stretching from present-day Senegal to al-Andalus in modern-day Spain. The city's stark, unadorned architecture reflects the strict religious beliefs of the Almoravids, who spread the Malikite rite of Sunni Islam throughout the Western Maghreb.

After two centuries of decline, the city was effectively re-founded in the 13th century as a fortified trading-center for nomadic trans-Saharan caravans, and as a means of connecting the Mediterranean with Sub-Saharan Africa. Although the walls of the original fortification disappeared centuries ago, many of the buildings in the old section of the city date from this period.

In 1996, UNESCO designated Chinguetti, along with the cities of Ouadane, Tichitt and Oualata, also in the dunes area, as a World Heritage Site.[3] Notable buildings in the town include The Friday Mosque of Chinguetti, an ancient structure of dry-stone construction, featuring a square minaret capped with five ostrich egg finials; the former French Foreign Legion fortress; and a tall watertower. The old quarter has five important manuscript libraries of scientific and Qur'anic texts, with many dating from the later Middle Ages. In recent years, the Mauritanian government, the U.S. Peace Corps, and various NGOs have attempted to position the city as a center for adventurous tourists. Visitors may "ski" down its sand dunes, visit the libraries, and appreciate the stark beauty of the Sahara.

The Friday Mosque is widely considered by Mauritanians to be the national symbol of the country.[1] The recently discovered offshore oilfield was named Chinguetti in its honor.